History

History of Abe Youan

Since 1731, when the first Abe Youan Sadatsuna became court physician to the Matsudaira clan, the Abe family has walked the path of medicine for over 290 years.

The Meaning Behind "Youan"

"You" (養) means to nurture and cultivate, while "An" (庵) represents a dwelling for those who pursue medicine.

The name "Youan" embodies the essence of medicine: nurturing people's health and protecting life.

This spirit has been passed down through ten generations since 1731, when the first Abe Youan Sadatsuna became court physician.

Chapter 1 1731~ Edo Period

Active Practice as Kampo Physicians

The first Abe Youan Sadatsuna (1699-1754) opened practice as a Kampo physician and was appointed as court physician to the Matsudaira clan on December 25, 1731.

Since then, the second generation Sadakazu, third generation Sadayoshi, fourth generation Sadamichi, and fifth generation Sadakazu served as court physicians to the Matsudaira clan, bearing the important responsibility of protecting the health of the feudal lord and his retainers.

The Abe family has continued to evolve with the times while inheriting the knowledge of Kampo medicine.

First Generation

Abe Youan Sadatsuna

1699-1754

Opened practice as court physician to the Matsudaira clan. Established the foundation of the Abe Youan family.

2nd-4th Generation

Sadakazu, Sadayoshi, Sadamichi

Served as court physicians for generations, inheriting the tradition of Kampo medicine.

Chapter 2 1846~ End of Edo Period

Aspiration for Advanced Medicine, The Fight Against Smallpox

The fifth Abe Youan Sadakazu made the decision to study Western medicine in addition to traditional Kampo medicine, foreseeing the transformation of the era.

He studied under Ogata Koan at <strong>Tekijuku</strong> in Osaka and mastered Dutch medicine, then learned surgical techniques at the <strong>Hanaoka School of Surgery</strong>. He acquired techniques from the lineage of Hanaoka Seishu, known for performing the world's first surgery under general anesthesia.

After returning home, he engaged in <strong>vaccination programs</strong> and devoted himself to preventing smallpox. As a practitioner of preventive medicine, he protected the lives of local people.

The fifth generation Sadakazu had a visionary philosophy of "integrating Eastern and Western medicine," which remains the origin of the research philosophy at Abe Youan Aging Research Institute today.

Chapter 3 1870~ Meiji Restoration

The Era of Separation of Medicine and Pharmacy

In the Meiji era, Western medicine became the mainstream of Japanese healthcare. Amid this major transformation, the Abe family forged a new path.

The sixth generation, Abe Minoru, <strong>passed the pharmacy licensing examination</strong> and operated a pharmaceutical business in Tokyo. The transition from physician to pharmacist was a strategic decision in response to the demands of the era.

The pharmaceutical tradition was passed on through the seventh generation, Abe Kazutomo, and the eighth generation, Abe Kazuo, establishing a new form of supporting people's health.

Sixth Generation

Abe Minoru

Passed the pharmacy licensing examination. Developed pharmaceutical business in Tokyo.

7th & 8th Generation

Abe Kazutomo & Abe Kazuo

Inherited the pharmaceutical tradition and strengthened the business foundation.

Chapter 4 1984~ Modern Era

The DNA of Abe Youan Lives On

The ninth generation, Abe Kazushige, encountered propolis in Brazil and recognized its potential. In 1984, he established <strong>Abe Youando Pharmaceuticals Co., Ltd.</strong> and expanded into the health food business.

In 2019, ahead of the industry, they began selling products featuring <strong>NMN (Nicotinamide Mononucleotide)</strong>. They continue to make pioneering efforts in the aging care field.

In 2023, the tenth generation, Abe Tomotaka, changed the company name to Abe Youando Pharmaceuticals Co., Ltd. And in 2025, <strong>the Abe Youan Aging Research Institute</strong> was established.

A new challenge has begun to realize the 290-year mission of "nurturing people's health" through cutting-edge geroscience research.

Ninth Generation

Abe Kazushige

1984 Established Abe Youando Pharmaceuticals

Encountered propolis in Brazil and started the health food business.

290 Years of History

1731 Kyoho 16

Foundation — Beginning as Court Physician

The first Abe Youan Sadatsuna was appointed as court physician to the Matsudaira clan. As a Kampo physician, he took on the role of protecting the health of the feudal lord and his retainers.

The Abe Youan Family in the Edo Period
1846 Koka 3

Tekijuku Enrollment — Origins of East-West Integration

The fifth generation, Abe Sadakazu, studied under Ogata Koan at Tekijuku in Osaka. He also trained at the Hanaoka School of Surgery, integrating Eastern and Western medicine.

Tekijuku Enrollment
1850s Ansei Period

Vaccination Program — Practice of Preventive Medicine

Sadakazu engaged in vaccination programs. To prevent smallpox, he promoted inoculation for local residents and protected their lives.

Vaccination Program
1870s Early Meiji

Transition to Pharmacy — Adapting to a New Era

The sixth generation, Abe Minoru, passed the pharmacy licensing examination. He developed pharmaceutical business in Tokyo.

Meiji Era
1984 Showa 59

Establishment of Abe Youando Pharmaceuticals

The ninth generation, Abe Kazushige, encountered propolis in Brazil and established Abe Youando Pharmaceuticals Co., Ltd.

Abe Youando Pharmaceuticals
2019 Reiwa 1

Launch of NMN Products

Ahead of the industry, they began selling products featuring NMN (Nicotinamide Mononucleotide).

NMN Products
2025 Reiwa 7

Establishment of Research Institute — A New Challenge

The tenth generation, Abe Tomotaka, established the Abe Youan Aging Research Institute. Realizing the 290-year mission through cutting-edge geroscience research.

Abe Youan Aging Research Institute

Inheritance of "Tradition × Science"

The approach of "fusion of tradition and innovation" demonstrated by the fifth generation Sadakazu is directly connected to the research philosophy of the current institute.

Era Tradition (Eastern Medicine) Science (Western Medicine / Modern Science)
Fifth Generation Era Knowledge of Kampo Medicine Dutch Medicine, Hanaoka Surgery, Vaccination
Modern Concepts of Mibyou and Youjou Geroscience, NMN, AI